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NEW: First Berlin Equity Research publishes updated research report on Cardiol Therapeutics in light of the Company’s recent Press Release announcing the initiation of the new pivotal study, MAVERIC-2 and phase II/III clinical trial within its development programme CardiolRx™ for the treatment of recurrent pericarditis (RP). MAVERIC-2 is expected to be initiated during Q4 at major pericardial disease centers in the United States and Europe and to report results ahead of the Company’s planned pivotal Phase III study in recurrent pericarditis.

The recent explosive success of prescription diabetic and weight loss drugs combined with a spike in acquisitions by Pfizer, Merck, and other large pharma giants is signaling a multi-billion-dollar buyout feeding frenzy in small biotechs.

This means the hunt is on for advanced clinical-stage drug developers holding key patent solutions related to obesity, diabetes, heart failure and other major cardiovascular issues.

A scenario that could place one small but fast-growing biotech dead center in the crosshairs of major pharmaceuticals on the lookout for developers of groundbreaking new medical solutions.

Cardiol Therapeutics Inc. (NASDAQ: CRDL), the “under-the-radar” biotech with two high-potential products in its current development pipeline was just granted coveted Orphan Drug Designation (ODD) status by the US FDA for its flagship therapeutic CardiolRx™ as a potential treatment for pericarditis. 
 
The designation hands Cardiol Therapeutics accelerated permissions and exclusive special rights from drug approval bodies to fast-track research and develop new medical treatments for rare disease markets. 

Peer Group Biotech Buyout…

This new ODD status combined with the company’s promising drug solutions in the development pipeline makes Cardiol Therapeutics a potentially enticing stand-alone play all on its own.

But what really pushes Cardiol Therapeutics Inc. (NASDAQ: CRDL) into the crosshairs of a high-potential buyout hunt is Novo Nordisk’s recent US$1.1 billion dollar purchase ¹  of Cardiol’s peer comparable, Cardior Pharmaceuticals

At the time of acquisition, Cardior Pharmaceuticals, a privately held developer of RNA-based solutions for heart failure, was in Phase 2 clinical trial for its lead asset, CDR132L.

In comparison, Cardiol Therapeutics has two ongoing Phase 2 clinical trials evaluating CardiolRx™ in rare heart diseases, and CRD-38 in pre-clinical development for heart failure.

Cardiol Therapeutics’ CRD-38

potential treatment for heart failure

is currently moving through pre-clinical trials,

and a promising solution couldn’t come soon enough.

With its flagship CardiolRx™ progressing though Phase 2 clinical trials, Cardiol Therapeutics Inc. (NASDAQ: CRDL) aims to provide promising effective treatments for those suffering from expensive, debilitating, and often deadly rare heart diseases.

Current treatments for recurrent pericarditis and acute myocarditis come with devastating costs considering…

Further complications stemming from acute myocarditis include heart failure, cardiogenic shock, unstable heart rhythm, cardiac arrest, and organ failure.

Currently, no FDA-approved therapies exist for acute myocarditis, leaving severe cases with drastic invasive options like pacemaker technologies and/or heart transplants

On the Hunt...

With Novo Nordisk’s acquisition of Cardior being just one of numerous recent high-profile buyouts of smaller drug development teams over the years, it’s obvious the major pharmaceutical giants are on the hunt for promising cardiovascular treatments considering…

Novo Nordisk’s large buyout sum for Cardior along with similarities between the two companies and offerings for treating heart diseases hasn’t gone unnoticed in the investment research community.

A recent independent research report by Leede Jones Gable  went so far as stating an implied market value for Cardiol Therapeutics Inc. (NASDAQ: CRDL) of US$16.14 a share, based on the value ascribed to Cardior.

REFERENCES
  1. https://www.reuters.com/markets/deals/novo-nordisk-buy-cardior-pharmaceuticals-up-11-bln-2024-03-25/
  2. Description pulled from: https://www.thermofisher.com/blog/behindthebench/what-is-an-oligo/
  3. https://www.cardiolrx.com/wp-content/uploads/2024/03/Cardiol-Therapeutics-%E2%80%93-Corporate-Presentation_March-2024.pdf
  4. https://leedejonesgable.com/wp-content/uploads/CRDL_2024_03_25.pdf